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Comparison of the Alpha and Beta Blocking Drug, Labetalol, and Methyl Dopa in the Treatment of Moderate and Severe Pregnancy-Induced Hypertension

1980; Informa; Volume: 2; Issue: 5 Linguagem: Inglês

10.3109/10641968009037147

0148-3927

G. D. Lamming, Fiona Broughton Pipkin, E. M. Symonds,

Hormonal Regulation and Hypertension

Twentysix women with pregnancy-induced hypertension have been randomly treated with either labetalol or Aldomet. A more satisfactory control of blood pressure was obtained with labetalol with minimal side-effects. After two weeks of treatment with labetalol renal function had significantly improved with a markedly lower incidence of proteinuria. More patients went into spontaneous labour following labetalol than following Aldomet; the Bishop score was also higher in this group. No adverse effects attributable to labetalol were noted in the baby either ante- or post-natally.