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Herpes Simplex Infection Causing Acute Necrotizing Tonsillitis

1994; Elsevier BV; Volume: 69; Issue: 3 Linguagem: Inglês

10.1016/s0025-6196(12)61067-2

1942-5546

Pamela Wat, John G. Strickler, Jeffrey L. Myers, MICHAEL R. NORDSTROM,

Musculoskeletal synovial abnormalities and treatments

ObjectiveTo describe the clinical and pathologic features of acute herpetic tonsillitis and to compare the histologic findings with those of herpetic lymphadenitis.DesignWe present a case report of a 22-year-old woman with bilateral cervical adenopathy, acute tonsillitis, and suspected peritonsillar abscess.Material and MethodsHistologic examination of the excised tonsils demonstrated discrete necrotic areas that contained cells with intranuclear viral inclusions.ResultsThe diagnosis of herpetic tonsillitis was confirmed by demonstrating herpes simplex virus (HSV)-infected cells on paraffin section immunostains and by positive HSV cultures of the tonsillar tissue.ConclusionHSV infection is an uncommon cause of acute tonsillitis; the histologic findings are similar to those seen in herpes simplex lymphadenitis. To describe the clinical and pathologic features of acute herpetic tonsillitis and to compare the histologic findings with those of herpetic lymphadenitis. We present a case report of a 22-year-old woman with bilateral cervical adenopathy, acute tonsillitis, and suspected peritonsillar abscess. Histologic examination of the excised tonsils demonstrated discrete necrotic areas that contained cells with intranuclear viral inclusions. The diagnosis of herpetic tonsillitis was confirmed by demonstrating herpes simplex virus (HSV)-infected cells on paraffin section immunostains and by positive HSV cultures of the tonsillar tissue. HSV infection is an uncommon cause of acute tonsillitis; the histologic findings are similar to those seen in herpes simplex lymphadenitis.