Portal de Periódicos da CAPES

Biological-Active Triterpenes of Alismatis Rhizoma. I. Isolation of the Alisols

1970; Pharmaceutical Society of Japan; Volume: 18; Issue: 7 Linguagem: Inglês

10.1248/cpb.18.1347

1347-5223

Tadakazu Murata, Yoshio Imai, T Hirata, Masuo Miyamoto,

Natural product bioactivities and synthesis

In order to isolate the hypocholesterolemic principle, the neutral ethyl acetatesoluble fraction of the methanol extract of Alismatis Rhizoma was fractionated in parallel with the biological test. Thus new compounds alisol A (1), alisol B (2), alisol A monoacetate (3), alisol B monoacetate (4) and alisol C monoacetate (5) were obtained. The compounds 1, 3, 4 and 5 were shown to be effective in the test with rats.