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Determination of human body burden baseline date of platinum through autopsy tissue analysis.

1976; National Institute of Environmental Health Sciences; Volume: 15; Linguagem: Inglês

10.1289/ehp.7615131

1552-9924

F Vandiver, F V Duffield, Anna M. Yoakum, Jacob R. Bumgarner, Jonathan Moran,

Effects and risks of endocrine disrupting chemicals

Results of analysis for platinum in 97 autopsy sets are presented. Analysis was performed by a specially developed emission spectrochemical method. Almost half of the individuals studied were found to have detectable platinum in one or more tissue samples. Platinum was found to be deposited in 13 of 21 tissue types investigated. Surprisingly high values were observed in subcutaneous fat, previously not considered to be a target site for platinum deposition. These data will serve as a human tissue platinum burden baseline in EPA's Catalyst Research Program.