Body size indices at different ages and epithelial ovarian cancer risk
2002; Elsevier BV; Volume: 38; Issue: 13 Linguagem: Inglês
10.1016/s0959-8049(02)00155-7
ISSN1879-0852
AutoresLuigino Dal Maso, Silvia Franceschi, Eva Negri, E. Conti, Marco Montella, Salvatore Vaccarella, Vincenzo Canzonieri, Fabio Parazzini, Carlo La Vecchia,
Tópico(s)Endometrial and Cervical Cancer Treatments
ResumoThe relationship between body mass measures at diagnosis and/or at different ages and ovarian cancer risk was investigated using an Italian multicentre case–control study. The study, conducted between 1992 and 1999, included 1031 cases of incident, histologically-confirmed epithelial ovarian cancer and 2411 controls admitted to the same network of hospitals for acute non-neoplastic conditions. Odds ratios (OR) and 95% confidence intervals (CI) were obtained using unconditional multiple logistic regression analyses. Weight and body mass index (BMI, kg/m2) 1 year prior to diagnosis/interview were not associated with ovarian cancer risk. A direct association emerged with waist-to-hip ratio (W/H) (OR=1.45 in the highest category), particularly among women with stage I-II cancers. Cases also had a higher BMI at age 30 years (OR=1.22). Conversely, cases had lower weight gain between age 30 years and the year prior to diagnosis/interview, both for cases with stage I-II and those with stage III-IV cancers.
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