Challenges and Opportunities in the Development of Organometallic Anticancer Drugs
2012; American Chemical Society; Volume: 31; Issue: 16 Linguagem: Inglês
10.1021/om300373t
ISSN1520-6041
AutoresChristian G. Hartinger, Nils Metzler‐Nolte, Paul J. Dyson,
Tópico(s)Synthesis and Biological Evaluation
ResumoThis review provides an introduction into the fascinating area of organometallic anticancer compounds. Although the subject dates back many years, it has witnessed considerable growth only in the past decade. A brief overview of the subject together with recent pertinent examples is provided. The properties of organometallic compounds that lend themselves to medical applications, the main current approaches used, and possible avenues for future research are identified.
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