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Artigo Revisado por pares
BIBTEX RIS

Development of morphine-induced changes of activity in the mouse

1981; Elsevier BV; Volume: 2; Issue: 4 Linguagem: Inglês

10.1016/0165-3806(81)90029-8

ISSN

1872-6755

Autores

Umberto Filibeck, Claudio Castellano, Alberto Oliverio,

Tópico(s)

Receptor Mechanisms and Signaling

Resumo

The development of spontaneous activity in response to morphine administration was studied at different postnatal ages in C57BL/6 mice. Morphine induced hyperactivity at all ages except in 3-week-old mice, in which a catatonic effect is evident. The results indicate that the neurophysiological and inhibitory systems responsible for the non-analgesic effects of morphine are not characterized by the same developmental pattern.

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