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Agarose as a tissue equivalent phantom material for NMR imaging

1986; Elsevier BV; Volume: 4; Issue: 3 Linguagem: Inglês

10.1016/0730-725x(86)91068-4

1873-5894

Matthew D. Mitchell, Harold L. Kundel, Leon Axel, Peter M. Joseph,

Atomic and Subatomic Physics Research

Phantoms for evaluation of nuclear magnetic resonance (NMR) imaging systems were made from water-based agarose gels, according to a standard procedure herein described. Copper sulfate (CuSO4) was included in the gels to further affect their proton relaxation characteristics. The proton relaxation rates of each batch of gel are dependent on the concentrations of agarose and copper ions in it, with T1 depending more on copper than on agarose, and T2 depending more strongly on agarose than on copper. The wide range of T1 and T2 which can be covered, and the stability and physical characteristics of the agarose gel material make it well-suited for phantom use.