Tumor classification and size in germ-cell testicular cancer. Influence on the occurrence of metastases
1982; Wiley; Volume: 50; Issue: 8 Linguagem: Inglês
10.1002/1097-0142(19821015)50
ISSN1097-0142
AutoresDerek Raghavan, Nicholas J. Vogelzang, George J. Bosl, Jane L. Torkelson, B. J. Kennedy, Lucien E. Nochomovitz, Juan Rosaí, Paul H. Lange, Elwin E. Fraley, Anne I. Goldman,
Tópico(s)Sperm and Testicular Function
ResumoCancerVolume 50, Issue 8 p. 1591-1595 ArticleFree Access Tumor classification and size in germ-cell testicular cancer. Influence on the occurrence of metastases Derek Raghavan MB, BS, FRACP, Derek Raghavan MB, BS, FRACP Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, Minnesota Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorNicholas J. Vogelzang MD, Nicholas J. Vogelzang MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorGeorge J. Bosl MD, George J. Bosl MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorJane Torkelson BSN, RN, Jane Torkelson BSN, RN Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorB. J. Kennedy MD, Corresponding Author B. J. Kennedy MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSection of Medical Oncology, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455===Search for more papers by this authorLucien E. Nochomovitz MD, Lucien E. Nochomovitz MD Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorJuan Rosai MD, Juan Rosai MD Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorPaul H. Lange MD, Paul H. Lange MD Department of Urologic Surgery, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorElwin E. Fraley MD, Elwin E. Fraley MD Department of Urologic Surgery, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorAnne Goldman PhD, Anne Goldman PhD School of Public Health, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this author Derek Raghavan MB, BS, FRACP, Derek Raghavan MB, BS, FRACP Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, Minnesota Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorNicholas J. Vogelzang MD, Nicholas J. Vogelzang MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorGeorge J. Bosl MD, George J. Bosl MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorJane Torkelson BSN, RN, Jane Torkelson BSN, RN Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorB. J. Kennedy MD, Corresponding Author B. J. Kennedy MD Department of Medicine, Section of Medical Oncology, University of Minnesota Medical School, Minneapolis, MinnesotaSection of Medical Oncology, Department of Medicine, University of Minnesota Medical School, Minneapolis, MN 55455===Search for more papers by this authorLucien E. Nochomovitz MD, Lucien E. Nochomovitz MD Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorJuan Rosai MD, Juan Rosai MD Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorPaul H. Lange MD, Paul H. Lange MD Department of Urologic Surgery, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorElwin E. Fraley MD, Elwin E. Fraley MD Department of Urologic Surgery, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this authorAnne Goldman PhD, Anne Goldman PhD School of Public Health, Section of Biometry, University of Minnesota Medical School, Minneapolis, MinnesotaSearch for more papers by this author First published: 15 October 1982 https://doi.org/10.1002/1097-0142(19821015)50:8 3.0.CO;2-5Citations: 32AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract The influence of local tumor spread (T-classification) and of tumor size on the occurrence of metastases was studied in 241 patients with testicular germ-cell neoplasms. All patients underwent thorough clinical or pathologic staging, or both, and were treated at the University of Minnesota Hospitals. Spread of tumor through the tunica vaginalis (T2) was associated with abdominal lymph node or distant metastases in eight of nine patients. Local tumor extension to the spermatic cord (T4a) was associated with metastatic spread in 29 of 31 men. Tumor size did not appear to correlate with metastatic rate. These findings are an important aid in designing adjuvant therapy trials and in establishing a "no treatment" approach after orchiectomy. References 1 Fraley EE, Lange PH, Kennedy BJ. Germ-cell testicular cancer in adults. 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Diagnostic techniques: Their strengths and weaknesses. Br J Cancer (Suppl) 1980; 41: 21–29. 15 Whitmore WF Jr. Surgical treatment of adult germinal testis tumors. Semin Oncol 1979; 6: 55–68. 16 Batata MA, Chu FCH, Hilaris BS, Whitmore WF, Grabstald H, Golbey R. TNM staging of testis cancer. Int J Radiat Oncol Biol Phys 1980; 6: 291–295. Citing Literature Volume50, Issue815 October 1982Pages 1591-1595 ReferencesRelatedInformation
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