Cholic-Acid-Based Fluorescent Sensor for Dicarboxylates and Acidic Amino Acids in Aqueous Solutions
2005; American Chemical Society; Volume: 7; Issue: 26 Linguagem: Inglês
10.1021/ol052341t
ISSN1523-7060
AutoresShunying Liu, Lei Fang, Yong-Bing He, Wing Hong Chan, Kai-Tai Yeung, Yuen‐Kit Cheng, Ronghua Yang,
Tópico(s)Analytical Chemistry and Chromatography
ResumoThe binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 106.
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