Portal de Periódicos da CAPES

Primary lung cancer in young patients: A study of 82 surgically treated patients

1992; Elsevier BV; Volume: 54; Issue: 1 Linguagem: Inglês

10.1016/0003-4975(92)91150-8

1552-6259

Philippe Icard, Jean‐François Régnard, S. De Napoli, A Rojas-Miranda, Philippe Dartevelle, P Levasseur,

Lung Cancer Research Studies

The aim of this study was to evaluate the prognosis for surgically treated young patients with primary lung cancer, a prognosis generally considered to be very poor.Eighty-two patients less than 40 years of age were operated on at Marie-Lannelongue Hospital between 1982 and 1990.There were 72 male and 10 female patients.Ten patients (12%) had never smoked, whereas 48 patients (59%) had smoked for more than 20 pack-years.The lung cancer was asymptomatic in 27 patients (33%) and symptomatic in the others.Adenocarcinoma was found in 42% of the patients, epidermoid carcinoma in 28%, mixed cell carcinoma in 16%, small cell carcinoma in 8.5%, and undifferentiated large cell carcinoma in 6%.Among the 69 resected tumors, 22 were stage I, ten were stage 11, 32 were stage IIIa, and five were stage IIIb.The resection was considered complete and curative in 56 patients ung cancer in patients less than 40 years of age has L been found by some authors [14] to have a poorer prognosis than does lung cancer in older patients.However, the prognosis for resected cancers in young patients is not well known because the cases are few in number, not exceeding 20 patients, in all published series [1-4].The aim of this study was to evaluate the prognosis of lung cancer in surgically treated patients less than 40 years of age and the factors that influence this prognosis. Patients and MethodsOur study is based on 82 patients less than 40 years of age operated on at Marie-Lannelongue Hospital between 1982 and 1990.The mean age of the patients was 35 years (range, 17 to 39 years).Five patients were less than 30 years old.There were 72 male and 10 female patients (male to female ratio, 7.2).These patients represented 2.2% of 3,700 patients who were operated on for primary lung cancer during this period.Ten patients (12%) had never smoked.Six patients had smoked for less than 10 pack-years; 8 patients, 10 to 20 pack-years; 16 patients, 20 to 30 pack-years; and 32 patients, more than 30 pack-years.