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A clinical and histopathologic study of granulomatous rosacea

1991; Elsevier BV; Volume: 25; Issue: 6 Linguagem: Inglês

10.1016/0190-9622(91)70304-k

1097-6787

Klaus F. Helm, Jennifer Menz, Lawrence E. Gibson, Charles H. Dicken,

Bartonella species infections research

A retrospective clinical and histopathologic study of 53 patients with granulomatous rosacea was undertaken. The patients had a broad clinical spectrum of lesions that ranged from primarily erythema to papulonodular lesions. Extrafacial lesions occurred in 15% of patients. Histologic examination showed mixed lymphohistiocytic inflammation (primarily lymphocytic inflammation in 40% of patients and primarily histiocytic with a few giant cells in 34%), epithelioid granulomas in 11% of patients, and epithelioid granulomas with caseation necrosis in 11%. Most patients had a good response to oral antibiotic therapy. Granulomatous rosacea is not a distinct disease but can be regarded and treated as a subtype of rosacea.