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HIV-1 Antiretroviral Drug Resistance in Recently Infected Patients in Abidjan, Côte d'Ivoire: A 4-Year Survey, 2002–2006

2007; Mary Ann Liebert, Inc.; Volume: 23; Issue: 9 Linguagem: Inglês

10.1089/aid.2007.0072

1931-8405

Thomas d’Aquin Toni, Bernard Masquelier, Albert Minga, Xavier Anglaret, Christine Danel, Ali Coulibaly, Henri Chenal, François Dabis, Roger Salamon, Hervé Fleury,

HIV/AIDS Research and Interventions

We performed HIV-1 drug resistance genotypic analysis of viral isolates from 100 antiretroviral (ARV)-naive, recently HIV-1-infected (between 2002 and 2006) individuals from Abidjan (Côte d'Ivoire). The overall prevalence of HIV-1 variants with resistance mutations to reverse transcriptase, protease, or fusion inhibitors was 6%. The majority of isolates were CRF02_AG. Compared with a previous study carried out by our group in 2001–2002 in a similar population in Abidjan, our findings confirm the circulation and transmission of HIV-1 carrying key ARV drug resistance mutation.