Produção Nacional
Revisado por pares
Distribution and heritability of diurnal preference (chronotype) in a rural Brazilian family-based cohort, the Baependi study
2015; Nature Portfolio; Volume: 5; Issue: 1 Linguagem: Inglês
10.1038/srep09214
ISSN2045-2322
AutoresMalcolm von Schantz, Tâmara P. Taporoski, Andréa R. V. R. Horimoto, Núbia E. Duarte, Homero Vallada, José Eduardo Krieger, Mário Pedrazzoli, André Brooking Negrão, Alexandre C. Pereira,
Tópico(s)Obesity, Physical Activity, Diet
ResumoAbstract Diurnal preference (chronotype) is a useful instrument for studying circadian biology in humans. It harbours trait-like dimensions relating to circadian period and sleep homeostasis, but also has ontogenetic components (morningness increases with age). We used the Morningness-Eveningness questionnaire (MEQ) in the Baependi study, a family-based cohort study based in a small town in Minas Gerais, Brazil. The population is highly admixed and has a cohesive and conservative lifestyle. 825 individuals (497 female) aged 18–89 years (average ± SD = 46.4 ± 16.3) and belonging to 112 different families participated in this study. The average MEQ score was 63.5 ± 11.2 with a significant (P < 0.0001) linear increase with age. Morningness was significantly (P < 0.0001) higher in the rural (70.2 ± 9.8) than in the municipal zone (62.6 ± 11.1) and was also significantly (P = 0.025) higher in male (64.6 ± 10.9) than in female (62.8 ± 11.2) participants. Thus, in spite of universal access to electricity, the Baependi population was strongly shifted towards morningness, particularly in the rural zone. Heritability of MEQ score was 0.48 when adjusted for sex and age, or 0.38 when adjusted for sex, age and residential zone. The reported MEQ score heritability is more akin to those of previous twin studies than previous family studies.
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