Natural‐Abundance 13 C‐NMR Spectroscopy of Two Glyco‐asparagines Derived from the Core of N ‐Glycosidic Carbohydrate Chains
1983; Wiley; Volume: 130; Issue: 1 Linguagem: Inglês
10.1111/j.1432-1033.1983.tb07124.x
ISSN1432-1033
AutoresBauke W. Dijkstra, Johannes F.G. Vliegenthart, Gérard Strecker, Jean Montreuil,
Tópico(s)Enzyme Structure and Function
Resumo13 C‐NMR spectroscopic studies were carried out on Manα(1→6)Manβ(1→4)GlcNAcβ(1→4)GlcNAcβ(1→N)‐Asn and Manα(1→6)Manβ(1→4)GlcNAcβ(1→4)[Fucα(1→6)]GlcNAcβ(1→N)Asn, which are part of the invariant core of N ‐glycosidically linked carbohydrates of glycoproteins. All resonances of proton‐bearing carbon atoms were unambiguously assigned. Where possible, the assignments were confirmed by selective proton‐decoupling experiments.
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