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Diseases and drugs but not food decrease ketoconazole ‘bioavailability’ [letter]

1990; Wiley; Volume: 29; Issue: 6 Linguagem: Inglês

10.1111/j.1365-2125.1990.tb03705.x

1365-2125

T K Daneshmend,

Diet and metabolism studies

British Journal of Clinical PharmacologyVolume 29, Issue 6 p. 783-784 Free Access Diseases and drugs but not food decrease ketoconazole ‘bioavailability’ [letter] TK Daneshmend, TK Daneshmend Department of Gastroenterology and Hepatology, University Hospital, Leiden, The Netherlands.Search for more papers by this author TK Daneshmend, TK Daneshmend Department of Gastroenterology and Hepatology, University Hospital, Leiden, The Netherlands.Search for more papers by this author First published: June 1990 https://doi.org/10.1111/j.1365-2125.1990.tb03705.xCitations: 8AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References Brass, C., Galgiani, J. N., Blaschke, T. F., Defelice, R., O'Reilly, R. A. & Stevens, D. A. (1982). Disposition of ketoconazole, an oral antifungal, in humans. Antimicrob. Agents Chemother., 27, 151–158. Carlson, J. A., Mann, H. J. & Canafax, D. D. (1983). Effect of pH on disintegration and dissolution of ketoconazole tablets. Am. J. Hosp. Pharm., 40, 1334–1336. Chapman, J. R. & Warnock, D. W. (1983). Ketoconazole and fungal CAPD peritonitis. Lancet, ii, 510–511. Daneshmend, T. K., Mason, A. R., Lowe, C. H., Warnock, D. W. & Johnson, E. M. (1986). Influence of formulation on ketoconazole pharmacokinetics in man: comparison of standard tablet vs capsule containing citric acid. J. Antimicrob. Chemother., 18, 289–291. Daneshmend, T. K., Warnock, D. W., Ene, M. D., Johnson, E. M., Potten, M. R., Richardson, M. D. & Williamson, P. J. (1984a). Absence of a food associated reduction in ketoconazole absorption at 200, 400, 600 and 800 mg doses in man. Br. J. clin. Pharmac., 17, 197P. Daneshmend, T. K., Warnock, D. W., Ene, M. D., Johnson, E. M., Potten, M. R., Richardson, M. D. & Williamson, P. J. (1984b). Influence of food on the pharmacokinetics of ketoconazole. Antimicrob. Agents Chemother., 25, 1–3. Donnelly, J. P., Starke, I. D., Galton, D. A. G., Catovsky, D., Goldman, J. M. & Darrell, J. H. (1984). Oral ketoconazole and amphotericin B for prevention of yeast colonization in patients with acute leukaemia. J. Hosp. Infect., 5, 83–93. Gascoigne, E. W., Barton, G. J., Michaels, M., Meuldermans, W. & Heykants, J. (1981). The kinetics of ketoconazole in animals and man. Clin. Res. Rev., 1, 177–187. Hann, I. M., Prentice, H. G., Keaney, M., Corringham, R., Blacklock, H. A., Fox, J., Gascoigne, E. & Van Cutsem, J. (1982). The pharmacokinetics of ketoconazole in severely immunocompromised patients. J. Antimicrob. Chemother., 10, 489–496. Lake-Bakaar, G., Cohen, P. & Strauss, E. W. (1988a). AIDS gastropathy: antibodies to gastric parietal cell. Gastroenterology, 94 (Part 2), A247. Lake-Bakaar, G., Tom, W., Gupta, N., Lake-Bakaar, D., Beidas, S., Elsakr, M. & Strauss, E. W. (1988b). AIDS gastropathy: reversible ketoconazole malabsorption. Gastroenterology, 94 (Part 2), A247. Mannisto, P. T., Mantyla, R., Nykanen, S., Lamminsivu, U. & Ottoila, P. (1982). Impairing effect of food on ketoconazole absorption. Antimicrob. Agents Chemother., 21, 730–733. Stockley, R. J., Daneshmend, T. K., Bredow, M. T., Warnock, D. W., Richardson, M. D. & Slade, R. R. (1986). Ketoconazole pharmacokinetics during chronic dosing in adults with haematological malignancy. Eur. J. clin. Microbiol., 5, 513–517. Sutherland, C., Murphy, J. E. & Schleifer, N. H. (1983). The effects of two gastric acidifying agents on the pharmacokinetics of ketoconazole. Abstract. The American Society of Hospital Pharmacists. 18th Annual Midyear Clinical Meeting, Atlanta, Georgia, December 4–8. Van der Meer, J. W. M., Keuning, J. J., Scheijgrond, H. W., Heykants, J. & Van Cutsem, J. (1980). Influence of gastric acidity on the bioavailability of ketoconazole. J. Antimicrob. Chemother., 6, 522–524. Vu Van, H., Piens, M. A., Archimbaud, E., Monier, M. F., Goyotat, D., Mojon, M. & Fiere, D. (1983). Serum levels of ketoconazole in bone marrow transplanted patients. Nouvelle Revue Française d'Hematologie, 25, 241–244. Winstanley, P. A. & Orme, M. L'E. (1989). The effects of food on drug bioavailability. Br. J. clin. Pharmac., 28, 621–628. Citing Literature Volume29, Issue6June 1990Pages 783-784 ReferencesRelatedInformation