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The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups

1987; Oxford University Press; Volume: 15; Issue: 2 Linguagem: Inglês

10.1093/nar/15.2.397

1362-4962

J.C. Schulhof, D. Molko, R. Téoule,

Chemical Synthesis and Analysis

Journal Article The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups Get access J.C. Schulhof, J.C. Schulhof Laboratoires de Chimie, Departement de Recherche Fondamentale, Centre d'Etudes Nucleaires de Grenoble85 X, F-38041 Grenoble Cedex, France Search for other works by this author on: Oxford Academic PubMed Google Scholar D. Molko, D. Molko Laboratoires de Chimie, Departement de Recherche Fondamentale, Centre d'Etudes Nucleaires de Grenoble85 X, F-38041 Grenoble Cedex, France Search for other works by this author on: Oxford Academic PubMed Google Scholar R. Teoule R. Teoule Laboratoires de Chimie, Departement de Recherche Fondamentale, Centre d'Etudes Nucleaires de Grenoble85 X, F-38041 Grenoble Cedex, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 15, Issue 2, 26 January 1987, Pages 397–416, https://doi.org/10.1093/nar/15.2.397 Published: 26 January 1987 Article history Received: 01 December 1986 Accepted: 19 December 1986 Published: 26 January 1987