The relationship between tremor and change in brain acetylcholine concentration produced by injection of tremorine or oxotremorine in the rat
1969; Wiley; Volume: 35; Issue: 2 Linguagem: Inglês
10.1111/j.1476-5381.1969.tb07988.x
ISSN1476-5381
Autores Tópico(s)Microtubule and mitosis dynamics
ResumoThe relationship between tremor and change in brain acetylcholine concentration after the injection of tremorine or oxotremorine has been investigated in rats. Tremorine produced a significant increase in whole brain acetylcholine and in tremor 5 min after injection. After this time tremor subsided but brain acetylcholine continued to increase. Oxotremorine produced tremor within 30 sec. This became maximal within 5 min of injection and then declined rapidly. The brain acetylcholine concentration showed a significant increase 5 min after injection and continued to increase until 30 min afterwards.
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