Synthetic studies towards forskolin
1989; Elsevier BV; Volume: 45; Issue: 5 Linguagem: Inglês
10.1016/0040-4020(89)80150-4
ISSN1464-5416
AutoresP. G. BARALDI, A. BARCO, Simonetta Benetti, V. Ferretti, G. P. POLLINI, Eleonora Polo, Vinicio Zanirato,
Tópico(s)Enzyme Catalysis and Immobilization
ResumoA model tricyclic system incorporating the complete array of oxygenated functions of the AB portion of forskolin has been synthetized. The highly substituted decalin unit of the natural target has been in turn assembled in a convenient way utilizing an intramolecular nitrile oxide cycloaddition reaction as key step.
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