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Prospective, Randomized Comparison of Same-Day Dose of 2 Different Bowel Cleanser for Afternoon Colonoscopy

2015; Wolters Kluwer; Volume: 94; Issue: 13 Linguagem: Inglês

10.1097/md.0000000000000628

1536-5964

Tae‒Geun Gweon, Sang Woo Kim, Yong-sun Noh, Seawon Hwang, Nayoung Kim, Yoonbum Lee, Soon-Wook Lee, Sung Won Lee, Jong Yul Lee, Chul‐Hyun Lim, Hyung Hun Kim, Jin Su Kim, Yu Kyung Cho, Jae Myung Park, In Seok Lee, Myung‐Gyu Choi,

Gallbladder and Bile Duct Disorders

For afternoon colonoscopy, same-day administration of sodium picosulfate, magnesium oxide, and citric acid (PM/Ca) is recommended. However, few studies have evaluated the bowel-cleansing efficacy and safety of this regimen. The aim of this study was to compare the bowel-cleansing efficacy, side effects, and patient's tolerability of a same-day split administration of PM/Ca with polyethylene glycol (PEG) for afternoon colonoscopy. Patients were randomly assigned to a PM/Ca group or a PEG group. The PM/Ca group consumed 1 sachet of PM/Ca at 06:00 and 1 sachet of PM/Ca 4 hours before the colonoscopy. They also took 2 tablets of bisacodyl before sleep on the night before. The PEG group consumed 2 L of PEG at 06:00 and 2 L of PEG 4 hours before the colonoscopy. All subjects were instructed to finish the bowel cleanser or fluid at least 2 hours before colonoscopy. All colonoscopic examinations were performed in the afternoon on the same day. The bowel-cleansing efficacy was scored using 2 scales: the Ottawa Bowel Preparation Scale (OBPS) and the Aronchick scale. Ease of using the bowel cleanser was rated from 1 (very easy) to 5 (very difficult). Two hundred nine patients underwent colonoscopy. The bowel-cleansing scores by OBPS did not differ between groups (5.0 vs 4.9, P = 0.63). Ease of using the bowel cleanser was superior in the PM/Ca group (P < 0.01). The cleansing efficacy of PM/Ca administered on the day of colonoscopy is comparable to that of PEG. Patients prefer PM/Ca.