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Review: Glucosamine and chondroitin, alone or in combination, do not clinically improve knee or hip pain in osteoarthritis

2011; American College of Physicians; Volume: 154; Issue: 6 Linguagem: Inglês

10.7326/0003-4819-154-6-201103150-02004

1539-3704

Joseph A. Markenson,

Osteoarthritis Treatment and Mechanisms

ACP Journal Club15 March 2011Review: Glucosamine and chondroitin, alone or in combination, do not clinically improve knee or hip pain in osteoarthritisJoseph A. Markenson, MD, FACP, MACPJoseph A. Markenson, MD, FACP, MACPJoan and Sanford Weill Medical College of Cornell University, New York, New York, USA (J.A.M.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-154-6-201103150-02004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationWandel S, Jüni P, Tendal B, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ. 2010;341:c4675. https://pubmed.ncbi.nlm.nih.gov/20847017Clinical Impact RatingsGIM/FP/GP: Phys Med & Rehab: Rheumatology: References1 Lumley T. Network meta-analysis for indirect treatment comparisons. Stat Med. 2002;21:2313-24. [PMID: 12210616] Google Scholar2 Replies to "Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis." www.bmj.com/content/341/bmj.c4675/reply (accessed 10 Jan 2011). Google Scholar3 Hochberg MC. Nutritional supplements for knee osteoarthritis—still no resolution [Editorial]. N Engl J Med. 2006;354:858-60. [PMID: 16495399] Google Scholar4 Zhang W, Nuki G, Moskowitz RW, et al. OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis Cartilage. 2010;18:476-99. [PMID: 20170770] Google Scholar5 Clegg DO, Reda DJ, Harris CL. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med. 2006;354:795-808. [PMID: 16495392] Google Scholar Author, Article, and Disclosure InformationAuthors: Joseph A. Markenson, MD, FACP, MACPAffiliations: Joan and Sanford Weill Medical College of Cornell University, New York, New York, USA (J.A.M.)This article was published at Annals.org on 1 March 2011. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySulfato de glucosamina y condroitín sulfato, fármacos para el tratamiento de la artrosis, acusados de no presentar eficacia clínica. ¿Culpables?Interpretation of Metaanalyses: Pitfalls Should Be More Widely RecognizedCuando las conclusiones del resumen son infundadas: Un caso de actuación ejemplar del British Medical Journal 15 March 2011Volume 154, Issue 6Page: JC3-4KeywordsAnalgesicsArthralgiaChondroitinDrugsHipKneesNetwork analysisOsteoarthritisSulfatesVisual analog scale ePublished: 15 March 2011 Issue Published: 15 March 2011 Copyright & PermissionsCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...