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BIBTEX RIS

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects.

1984; BMJ; Volume: 39; Issue: 7 Linguagem: Inglês

10.1136/thx.39.7.500

ISSN

1468-3296

Autores

Neil Barnes, Priscilla J. Piper, John Costello,

Tópico(s)

Infant Health and Development

Resumo

The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways.

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