Staphylococcus aureus Infection as a Complication of Isotretinoin Therapy

1987; American Medical Association; Volume: 123; Issue: 5 Linguagem: Inglês

10.1001/archderm.1987.01660290074019

ISSN

1538-3652

Autores

William D. James,

Tópico(s)

Oral Health Pathology and Treatment

Resumo

Eighteen patients developed Staphylococcus aureus infection during or shortly after a five-month course of therapy with isotretinoin. Staphylococcus aureus was recovered both from lesions and from the anterior nares. In a prospective study, 4% of control patients treated with isotretinoin alone developed S aureus infection, while none who applied topical antibiotic to the anterior nares developed infection. Control patients had a 64% prevalence of anterior nares colonization with S aureus, compared with 18% in the topical antibiotic group.

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