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Epidemiology of amyotrophic lateral sclerosis in Hordaland county, western Norway

1991; Wiley; Volume: 83; Issue: 5 Linguagem: Inglês

10.1111/j.1600-0404.1991.tb04701.x

1600-0404

Ole‐Bjørn Tysnes, Dan J. Stein, Johan A. Aarli,

Neurogenetic and Muscular Disorders Research

Acta Neurologica ScandinavicaVolume 83, Issue 5 p. 280-285 Epidemiology of amyotrophic lateral sclerosis in Hordaland county, western Norway O.-B. Tysnes, Corresponding Author O.-B. Tysnes Department of Neurology, University of Bergen School of Medicine, Haukeland Sykehus, NorwayOle-Bjørn Tysnes, Department of Neurology, Haukeland Sykehus, N-5021 Bergen, NorwaySearch for more papers by this authorS. E. Vollset, S. E. Vollset Section for Medical Informatics and Statistics, University of Bergen School of Medicine, Haukeland Sykehus, NorwaySearch for more papers by this authorJ. A. Aarli, J. A. Aarli Department of Neurology, University of Bergen School of Medicine, Haukeland Sykehus, NorwaySearch for more papers by this author O.-B. Tysnes, Corresponding Author O.-B. Tysnes Department of Neurology, University of Bergen School of Medicine, Haukeland Sykehus, NorwayOle-Bjørn Tysnes, Department of Neurology, Haukeland Sykehus, N-5021 Bergen, NorwaySearch for more papers by this authorS. E. Vollset, S. E. Vollset Section for Medical Informatics and Statistics, University of Bergen School of Medicine, Haukeland Sykehus, NorwaySearch for more papers by this authorJ. A. Aarli, J. A. Aarli Department of Neurology, University of Bergen School of Medicine, Haukeland Sykehus, NorwaySearch for more papers by this author First published: May 1991 https://doi.org/10.1111/j.1600-0404.1991.tb04701.xCitations: 46AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The incidence, prevalence and prognosis of amyotrophic lateral sclerosis (ALS) in the county of Hordaland, western Norway were determined for the years 1978 through 1988. The average annual incidence rate was 1.60 per 100000 population with a male to female ratio of 1.26 (95% confidence interval: 0.76–2.09). The maximal age-specific annual incidence was 8.12 per 100000 and occurred in the age-group between 61 and 65 years. The prevalence of ALS was 3.67 per 100000 on December 31, 1988. The average age at the onset of the disease was 60.9 years ranging from 34 to 82 years of age. Survival was studied with life table techniques. Median survival from the onset of symptoms was 28.0 months overall. In patients with bulbar onset the median survival was 24.0 months whereas it was 40 months in patients with spinal onset of disease (log rank test, P = 0.0004). The difference in survival between ALS with bulbar or spinal onset was not explained by age or sex differences in the two groups. Citing Literature Volume83, Issue5May 1991Pages 280-285 RelatedInformation