Rapid Lung Volumetry Using Ultrafast Dynamic Magnetic Resonance Imaging During Forced Vital Capacity Maneuver
2007; Lippincott Williams & Wilkins; Volume: 42; Issue: 1 Linguagem: Inglês
10.1097/01.rli.0000250735.92266.6b
ISSN1536-0210
AutoresAndy Swift, Neil Woodhouse, Stan Fichele, Jochen Siedel, Gary Mills, Edwin J.R. van Beek, Jim M. Wild,
Tópico(s)MRI in cancer diagnosis
ResumoDynamic magnetic resonance imaging (MRI) has the potential for rapid noninvasive evaluation of changes in lung volume. The aim of this study was to perform rapid lung volumetry using ultrafast dynamic MRI to capture a forced vital capacity (FVC) maneuver.Nine healthy volunteers underwent 2-dimensional spoiled gradient echo imaging in coronal and sagittal planes during FVC maneuvers. An elliptical model of the axial cross section of the lungs was used to generate rapid volume-time curves. Spirometric indices were correlated with MR volumetry findings.Total lung volume calculated from static MRI correlated well with the dynamic MR scans (r = 0.83; P < 0.01). Spirometric indices (first second of forced expiration and FVC) calculated from our MR volumetry technique correlated well with conventional spirometry (P < 0.01).The technique provides a means of sampling lung volume change during the rapid subsecond movements that take place during a FVC maneuver.
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