Nail matrix biopsy of longitudinal melanonychia: Diagnostic algorithm including the matrix shave biopsy
2007; Elsevier BV; Volume: 56; Issue: 5 Linguagem: Inglês
10.1016/j.jaad.2006.12.001
ISSN1097-6787
Autores Tópico(s)Plant Pathogens and Fungal Diseases
ResumoLongitudinal melanonychia (LM) may represent nail matrix melanocyte activation (defined as a normal number of melanocytes with increased production of melanin), benign hyperplasia, or melanoma, in addition to multiple nonmelanocyte pathologies, including hemorrhage and infection. This article details an algorithmic approach to LM, including a careful history and physical examination, dermoscopy, and ability to sample the matrix using 3 biopsy techniques, a 3-mm punch excision, a lateral longitudinal excision, and a matrix shave biopsy. Facility with all 3 techniques will allow the physician to procure appropriate nail matrix specimens for diagnosis.
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