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Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer

2002; Massachusetts Medical Society; Volume: 347; Issue: 16 Linguagem: Inglês

10.1056/nejmoa022152

1533-4406

Bernard Fisher, Stewart Anderson, John Bryant, Richard G. Margolese, Melvin Deutsch, Edwin R. Fisher, Jong‐Hyeon Jeong, Norman Wolmark,

Breast Implant and Reconstruction

In 1976, we initiated a randomized trial to determine whether lumpectomy with or without radiation therapy was as effective as total mastectomy for the treatment of invasive breast cancer.