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Application of the Grubbs Ring-Closure Olefin Metathesis in the Synthesis of Trans-Fused Oxacycles

1997; Elsevier BV; Volume: 38; Issue: 35 Linguagem: Inglês

10.1016/s0040-4039(97)01412-3

1873-3581

Mercedes Delgado, Julio D. Martı́n,

Marine Toxins and Detection Methods

A highly efficient and flexible route to trans-fused oxacycles is outlined, which is based on the formation of seven-, eight-, and nine-membered oxacycles by ring-closing metathesis (RCM) as the key step. © 1997 Elsevier Science Ltd.