Artigo Revisado por pares

Towards Artificial Ion Channels: Transport of Alkali Metal Ions across Liposomal Membranes by “Bouquet” Molecules

1992; Wiley; Volume: 31; Issue: 12 Linguagem: Inglês

10.1002/anie.199216371

ISSN

1521-3773

Autores

Marko J. Pregel, Ludovic Jullien, Jean‐Maríe Lehn,

Tópico(s)

Lipid Membrane Structure and Behavior

Resumo

If "bouquet" molecules with a central crown ether or cyclodextrin unit and poly(oxyethylene) or polymethylene arms are built into the membranes of liposomes (as shown in the diagram), Na+ and Li+ ions can be transported across the membrane. All the results are consistent with a channel transport mechanism.

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