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Diphenylcarbamoyl and propionyl groups: a new combination of protecting groups for the guanine residue

1983; Elsevier BV; Volume: 24; Issue: 27 Linguagem: Inglês

10.1016/s0040-4039(00)88019-3

1873-3581

Takashi Kamimura, Masahiko Tsuchiya, K. KOURA, Mitsuo Sekine, Tsujiaki Hata,

Molecular Sensors and Ion Detection

Protection of the guanine residue with the O5-diphenylcarbamoyl and N2-propionyl groups is described. These protecting groups could be readily introduced and removed simultaneously. They were used to demonstrate the synthesis of the deoxyguanylate dimer in high yield.