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Sarcoidosis after Antiretroviral Therapy in a Patient with Acquired Immunodeficiency Syndrome

2000; Oxford University Press; Volume: 31; Issue: 5 Linguagem: Inglês

10.1086/317422

1537-6591

Víctor Jacinto Ovejero Gómez, P. R. Smith, Jedidiah Burack, Raymond Daley, U. Rosa,

Drug-Induced Adverse Reactions

A 53-year-old man with acquired immunodeficiency syndrome (AIDS) developed clinical and radiological features compatible with sarcoidosis 14 months after starting highly active antiretroviral therapy (HAART). The CD4 lymphocyte count had increased from 5 cells/mm3 to 235 cells/mm3 with HAART. Transbronchial lung biopsy showed nonnecrotizing granulomas. All studies for an infectious etiology were negative. His condition improved after treatment with corticosteroids. To our knowledge, this is the fifth case report of sarcoidosis occurring after initiation of antiretroviral therapy for AIDS.