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A Phase I Study of Recombinant Adenovirus Vector-Mediated Delivery of an Anti-erbB-2 Single-Chain (sFv) Antibody Gene for Previously Treated Ovarian and Extraovarian Cancer Patients. University of Alabama at Birmingham, Birmingham, Alabama

1997; Mary Ann Liebert, Inc.; Volume: 8; Issue: 2 Linguagem: Inglês

10.1089/hum.1997.8.2-229

1557-7422

Ronald D. Alvarez, David T. Curiel,

Viral Infectious Diseases and Gene Expression in Insects

Human Gene TherapyVol. 8, No. 2 News and CommentsA Phase I Study of Recombinant Adenovirus Vector-Mediated Delivery of an Anti-erbB-2 Single-Chain (sFv) Antibody Gene for Previously Treated Ovarian and Extraovarian Cancer Patients. University of Alabama at Birmingham, Birmingham, AlabamaSTUDY CHAIRMEN Ronald D. Alvarez and David T. CurielSTUDY CHAIRMEN Ronald D. AlvarezSearch for more papers by this author and David T. CurielSearch for more papers by this authorPublished Online:20 Mar 2008https://doi.org/10.1089/hum.1997.8.2-229AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited byState of play and clinical prospects of antibody gene transfer7 June 2017 | Journal of Translational Medicine, Vol. 15, No. 1Gene Therapy in the Treatment of Human Cancer13 November 2016HER2/neu: an increasingly important therapeutic target. Part 3: clinical applications and investigationsClinical Investigation, Vol. 4, No. 9Role of RGD-containing ligands in targeting cellular integrins: Applications for ovarian cancer virotherapy1 March 2010 | Experimental and Therapeutic Medicine, Vol. 1, No. 2Intracellular Antibodies (Intrabodies) and Their Therapeutic PotentialIonizing radiation enhances adenoviral vector expressingmda-7/IL-24-mediated apoptosis in human ovarian cancer1 January 2006 | Journal of Cellular Physiology, Vol. 208, No. 2Infectivity enhanced adenoviral-mediated mda-7/IL-24 gene therapy for ovarian carcinomaGynecologic Oncology, Vol. 94, No. 2A Multicenter Phase I Gene Therapy Clinical Trial Involving Intraperitoneal Administration of E1A-Lipid Complex in Patients with Recurrent Epithelial Ovarian Cancer Overexpressing HER-2/ neu Oncogene6 May 2004 | Clinical Cancer Research, Vol. 10, No. 9Ablating CAR and Integrin Binding in Adenovirus Vectors Reduces Nontarget Organ Transduction and Permits Sustained Bloodstream Persistence Following Intraperitoneal AdministrationMolecular Therapy, Vol. 9, No. 2Regulatory and Legal Requirements for the Manufacture of AntibodiesGene Therapy of Ovarian Cancer—State-of-the-Art and Future PerspectivesGene Therapy in the Treatment of Human CancerAdenoviruses in OncologyBioDrugs, Vol. 16, No. 2Untangling the ErbB signalling network1 February 2001 | Nature Reviews Molecular Cell Biology, Vol. 2, No. 2Transient Transgenesis in The Endocrine System: Viral Vectors for Gene DeliveryUsing a Tropism-Modified Adenoviral Vector to Circumvent Inhibitory Factors in Ascites Fluid Jerry L. Blackwell, Hui Li, Jesus Gomez-Navarro, Igor Dmitriev, Victor Krasnykh, Christy A. Richter, Denise R. Shaw, Ronald D. Alvarez, David T. Curiel, and Theresa V. Strong6 July 2004 | Human Gene Therapy, Vol. 11, No. 12The ErbB/HER family of receptor tyrosine kinases: A potential target for chemoprevention of epithelial neoplasmsJournal of Cellular Biochemistry, Vol. 77, No. S34An Advanced Generation of Adenoviral Vectors Selectively Enhances Gene Transfer for Ovarian Cancer Gene Therapy ApproachesGynecologic Oncology, Vol. 74, No. 2Variables Affecting the Transduction Efficiency of Adenovirus Vectors in Bovine Aortic Endothelial CellsThrombosis Research, Vol. 93, No. 1Biochemical and Clinical Implications of the ErbB/HER Signaling Network of Growth Factor ReceptorsAn Adenovirus Vector with Genetically Modified Fibers Demonstrates Expanded Tropism via Utilization of a Coxsackievirus and Adenovirus Receptor-Independent Cell Entry MechanismJournal of Virology, Vol. 72, No. 12Intracellular Antibody-Mediated Knockout of the ErbB-2 Oncoprotein as a Cancer Gene Therapy ApproachAdvances in adenoviral vectors for cancer gene therapy25 February 2005 | Expert Opinion on Therapeutic Patents, Vol. 7, No. 12A Single Chain Fv Fragment of P-glycoprotein-specific Monoclonal Antibody C219Journal of Biological Chemistry, Vol. 272, No. 47 Volume 8Issue 2Jan 1997 InformationCopyright 1997, Mary Ann Liebert, Inc.To cite this article:STUDY CHAIRMEN Ronald D. Alvarez and David T. Curiel.A Phase I Study of Recombinant Adenovirus Vector-Mediated Delivery of an Anti-erbB-2 Single-Chain (sFv) Antibody Gene for Previously Treated Ovarian and Extraovarian Cancer Patients. University of Alabama at Birmingham, Birmingham, Alabama.Human Gene Therapy.Jan 1997.229-242.http://doi.org/10.1089/hum.1997.8.2-229Published in Volume: 8 Issue 2: March 20, 2008PDF download