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Transmission of Hepatitis C Virus to Spouses

1995; American College of Physicians; Volume: 122; Issue: 2 Linguagem: Inglês

10.7326/0003-4819-122-2-199501150-00015

1539-3704

Eveline P. Mauser‐Bunschoten, Dorine Bresters, H. W. Reesink,

Hepatitis C virus research

Letters15 January 1995Transmission of Hepatitis C Virus to SpousesEveline P. Mauser-Bunschoten, Dorine Bresters, and Henk W. ReesinkEveline P. Mauser-BunschotenSearch for more papers by this author, Dorine BrestersSearch for more papers by this author, and Henk W. ReesinkSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-2-199501150-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Akahane and colleagues [1] reported that 27% of spouses of patients with hepatitis C virus (HCV) infection had antibodies against HCV and that 18% of the spouses were positive for HCV RNA. Bresters and colleagues [2] observed no sexual transmission in 50 heterosexual partners of index patients positive for HCV RNA who had had unprotected sexual intercourse for a total of 713 person-years (mean duration per couple, 13 years). In this study [2], branched-chain DNA assay showed that index patients had an HCV RNA titer ranging from below the cutoff to 626 × 105 eq/mL, which is ...References1. Akahane Y, Kojima M, Sugai Y, Sakamoto M, Miyazaki Y, Tanaka T, et al. Hepatitis C virus infection in spouses of patients with type C chronic liver disease. Ann Intern Med. 1994; 120:748-52. Google Scholar2. Bresters D, Mauser-Bunschoten EP, Reesink HW, Roosendaal G, van der Poel CL, Chamuleau RA, et al. Sexual transmission of hepatitis C. Lancet. 1993; 342:210-1. Google Scholar3. Hsu HH, Wright TL, Luba D, Martin M, Feinstone SM, Garcia G, et al. Failure to detect hepatitis C virus genome in human secretions with the polymerase chain reaction. Hepatology. 1991; 14:763-7. Google Scholar4. Zaayer HL, Cuypers HT, Reesink HW, Winkel IN, Gerken G, Lelie PN. Reliability of polymerase chain reaction for detection of hepatitis C virus. Lancet. 1992; 341:722-4. Google Scholar Author, Article, and Disclosure InformationAuthors: Eveline P. Mauser-Bunschoten; Dorine Bresters; Henk W. ReesinkAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHepatitis C: an epidemiological reviewSexual Transmission of Hepatitis C Virus and Prevention with Intramuscular ImmunoglobulinHepatitis C 15 January 1995Volume 122, Issue 2Page: 154-155KeywordsAntibodiesHemophiliaHepatitis C virusHeterosexualsInfectious hepatitisMedical risk factorsPolymerase chain reactionRNASpecificityViral load ePublished: 15 August 2000 Issue Published: 15 January 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...