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Comparison of Non-breath-hold High Resolution Gadolinium-enhanced MRA with Digital Subtraction Angiography in the Evaluation on Allograft Renal Artery Stenosis

2001; Elsevier BV; Volume: 56; Issue: 2 Linguagem: Inglês

10.1053/crad.2000.0590

1365-229X

Y. L. Chan, Chi Bon Leung, Simon C.H. Yu, David K.W. Yeung, Philip Kam‐Tao Li,

Advanced MRI Techniques and Applications

Abstract AIM: The study objective was to compare the diagnostic accuracy of non-breath-hold high resolution gadolinium-enhanced magnetic resonance angiography (Gd-MRA) with intra-arterial digital subtraction angiography (DSA) in the evaluation of allograft renal artery stenosis (ARAS). MATERIALS AND METHODS: We studied 17 renal transplant recipients (six men, 11 women, age 34–64 years) with a systolic bruit in the transplant region beyond the early post-operative period. Gadolinium–enhanced magnetic resonance angiography was performed by non-breath-hold high resolution 3D acquisition in the oblique coronal plane using a 256 × 512 matrix. Digital subtraction angiography was performed with AP and oblique views and ARAS was graded as ≤50% or >50% diameter stenosis on the view that displayed the maximal narrowing. RESULTS: Digital subtraction angiography showed >50% stenosis in seven patients, all of whom were diagnosed correctly on Gd-MRA. Gadolinium-enhanced magnetic resonance angiography diagnosed two patients with >50% stenosis which were not confirmed on DSA. Eight patients had no or ≤50% stenosis on both Gd-MRA and DSA. The sensitivity and specificity of Gd-MRA in revealing >50% stenosis were 100% and 75%, respectively, using DSA as the gold standard. CONCLUSION: High resolution Gd-MRA employing a non-breath-hold technique is highly sensitive in the diagnosis of ARAS greater than 50%. It is preferred as a non-invasive screening technique to DSA in suspected ARAS.Chan, Y. L. (2001). Clinical Radiology 56, 127–132.