Voltar
Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Circulatory and Ventilatory Power: Characterization in Patients with Coronary Artery Disease

2015; Sociedade Brasileira de Cardiologia (SBC); Linguagem: Inglês

10.5935/abc.20150035

ISSN

1678-4170

Autores

Viviane Castello‐Simões, Vinícius Minatel, Marlus Karsten, Rodrigo Polaquini Simões, Natália Maria Perseguini, Juliana Cristina Milan, Ross Arena, Laura Maria Tomazi Neves, Audrey Borghi‐Silva, Aparecida Maria Catai,

Tópico(s)

Cardiac Health and Mental Health

Resumo

Background: Circulatory power (CP) and ventilatory power (VP) are indices that have been used for the clinical evaluation of patients with heart failure; however, no study has evaluated these indices in patients with coronary artery disease (CAD) without heart failure.Objective: To characterize both indices in patients with CAD compared with healthy controls.Methods: Eighty-seven men [CAD group = 42 subjects and healthy control group (CG) = 45 subjects] aged 40-65 years were included.Cardiopulmonary exercise testing was performed on a treadmill and the following parameters were measured: 1) peak oxygen consumption (VO 2 ), 2) peak heart rate (HR), 3) peak blood pressure (BP), 4) peak rate-pressure product (peak systolic HR x peak BP), 5) peak oxygen pulse (peak VO 2 /peak HR), 6) oxygen uptake efficiency (OUES), 7) carbon dioxide production efficiency (minute ventilation/carbon dioxide production slope), 8) CP (peak VO2 x peak systolic BP) and 9) VP (peak systolic BP/carbon dioxide production efficiency).Results: The CAD group had significantly lower values for peak VO 2 (p < 0.001), peak HR (p < 0.001), peak systolic BP (p < 0.001), peak rate-pressure product (p < 0.001), peak oxygen pulse (p = 0.008), OUES (p < 0.001), CP (p < 0.001), and VP (p < 0.001) and significantly higher values for peak diastolic BP (p = 0.004) and carbon dioxide production efficiency (p < 0.001) compared with CG.Stepwise regression analysis showed that CP was influenced by group (R 2 = 0.44, p < 0.001) and VP was influenced by both group and number of vessels with stenosis after treatment (interaction effects: R 2 = 0.46, p < 0.001).Conclusion: The indices CP and VP were lower in men with CAD than healthy controls.(

Referência(s)