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Six New 2-(2-Phenylethyl)chromones from Agarwood.

2002; Pharmaceutical Society of Japan; Volume: 50; Issue: 3 Linguagem: Inglês

10.1248/cpb.50.419

1347-5223

Tenji Konishi, Takao Konoshima, Yasuo Shimada, Shiu Kiyosawa,

Biological Stains and Phytochemicals

Six new chromones, 6-methoxy-2-[2-(3-methoxy-4-hydroxyphenyl)ethyllchromone (2), 6,8-dihydroxy-2-(2-phenylethyl)chromone (3), 6-hydroxy-2-[2-(4-hydroxyphenyl)ethyl]chromone (4), 6-hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone (5), 7-hydroxy-2-(2-phenylethyl)chromone (6), and 6-hydroxy-7-methoxy-2-(2-phenylethyl)chromone (7) were isolated from the ether extract of agarwood in addition to a known compound, 2-(2-phenylethyl)chromone or flidersiachromone (1). Their structures were determined by spectroscopic methods including UV, IR, and NMR spectral data and comparisons with the calculated values using the hydroxyl and methoxyl substituent increments of the chromone ring.