Genetic analysis of isolation-induced aggression I. Comparison between closely related inbred mouse strains

1992; Academic Press; Volume: 57; Issue: 3 Linguagem: Inglês

10.1016/0163-1047(92)90150-3

ISSN

1557-8003

Autores

Regine Schneider, Hans-Jürgen Hoffmann, Horst Schicknick, R Moutier,

Tópico(s)

Genetic Mapping and Diversity in Plants and Animals

Resumo

Young adult males of the inbred mouse strains BALB/c, C57BL/6, CBA, C3H/He, and the outbred strain NMRI showed significant interstrain differences for isolation-induced aggression as measured in a standard-opponent test. Additionally, four related inbred strains of common origin (ABG, AB//Halle, ABB, AB//Jena) were studied. ABG and AB//Halle showed nearly no overlap for the trait isolation-induced aggression. Tests of histocompatibility and coat color, as well as mandible measurements, confirmed a close genetic relationship between ABG and AB//Halle. The large difference for isolation-induced aggression between these two closely related strains offers excellent opportunities to search for single gene correlates of aggression.

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