Portal de Periódicos da CAPES

Artigo Produção Nacional Revisado por pares

BIBTEX RIS

The Impact of Photodynamic Therapy on the Viability of Streptococcus mutans in a Planktonic Culture

2007; Mary Ann Liebert, Inc.; Volume: 25; Issue: 6 Linguagem: Inglês

10.1089/pho.2007.2109

1557-8550

Isabela Bevilacqua, Renata Amadei Nicolau, Sônia Khouri, Aldo Brugnera, Guilherme Rodrigues Teodoro, Renato Amaro Zângaro, Marcos Tadeu Tavares Pacheco,

Nanoplatforms for cancer theranostics

This study investigated the effect of photodynamic therapy (PDT) with toluidine blue O (TBO) and a light-emitting diode (LED) on the viability of Streptococcus mutans cells in a planktonic culture.Growth of Streptococcus mutans is the first step in the development of tooth decay. The use of light and dyes promotes cellular death in a noninvasive way, reducing treatment time.The LED used in this study had output power of 116 mW, its energy was 21 J, and the fluency was 2.18 J/cm(2). Samples were prepared and divided into five groups: (1) control group (-); (2) control group (+); (3) TBO; (4) LED; and (5) LED + TBO.One hundred percent of the bacteria were killed following irradiation with LED and TBO. The biofilm that formed on the glass surfaces was analyzed by SEM and colony count.It was demonstrated that PDT was efficient at killing microorganisms and preventing the formation of biofilms.