Persistent polyclonal B-cell lymphocytosis
1994; Elsevier BV; Volume: 18; Issue: 10 Linguagem: Inglês
10.1016/0145-2126(94)90062-0
ISSN1873-5835
AutoresSamit Agrawal, Estella Matutes, J Voke, Martin J.S. Dyer, Tariq Khokhar, Daniel Catovsky,
Tópico(s)Lymphoma Diagnosis and Treatment
ResumoWe document a case of persistent lymphocytosis in which the characteristic binucleated circulating lymphocytes were shown immunologically to be polyclonal B-cells. Cytogenetic and molecular studies failed to show a clonal population. A review of the literature on this rare condition, persistent polyclonal B-cell lymphocytosis, highlights an association with the female sex, HLA-DR7 antigen, smoking and raised levels of IgM, all of which were present in our patient.
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