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Emerging acute Chagas Disease in Amazonian Brazil: case reports with serious cardiac involvement

2004; Elsevier BV; Volume: 8; Issue: 6 Linguagem: Inglês

10.1590/s1413-86702004000600010

1678-4391

Ana Yecê das Neves Pinto, Sebastião Aldo da Silva Valente, Vera da Costa Valente,

Viral Infections and Immunology Research

Four cases of serious cardiac attacks by autochthonous Trypanosoma cruzi infection from the Brazilian Amazon are reported; three of them occurred in micro-epidemic episodes. The manifestations included sudden fever, myalgia, dyspnea and signs of heart failure. Diagnosis was confirmed by specific exams, especially QBC (Quantitative Buffy Coat) and natural xenodiagnosis. Despite treatment with benznidazol, three patients died with serious myocarditis, renal failure and cardiac tamponade. The authors call attention to the emergence of this disease and reveal a previously unknown pathogenicity of T. cruzi strains in this area, added to a non-usual transmission form.