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Doença de Castleman ou hiperplasia angiofolicular como nódulo pulmonar solitário: relato de caso

2007; Sociedade Brasileira de Pneumologia e Tisiologia; Volume: 33; Issue: 2 Linguagem: Inglês

10.1590/s1806-37132007000200019

1806-3756

Guilherme Andrade Krawczun, Cristiano de Morais Garcia, Kazuhiro Ito, Olavo Franco Ferreira Filho, João Carlos Thomson,

Eosinophilic Disorders and Syndromes

Castleman's disease is a rare disorder generally characterized by a mediastinal nodule, with a great variety of alternative presentations regarding age, clinical manifestations and evolution. This case report describes a 40-year-old female patient presenting with uncharacteristic chest pain for a few years. A chest X-ray revealed a hypotransparency on the right side. Computed tomography and pulmonary arteriography did not elucidate the diagnosis, which was made through surgical resection and anatomopathological examination of the nodule, which presented characteristics of angiofollicular hyperplasia, or Castleman's disease. This article emphasizes the importance of adding this disease to the list of morbidities in the differential diagnosis of pulmonary solitary nodules.