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BIBTEX RIS

In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSe x S 2– x )/ZnS Core/Shell Quantum Dots

2013; American Chemical Society; Volume: 13; Issue: 9 Linguagem: Inglês

10.1021/nl402054w

ISSN

1530-6992

Autores

Matthew G. Panthani, Tarik A. Khan, Dariya K. Reid, Daniel J. Hellebusch, Michael Rasch, Jennifer A. Maynard, Brian A. Korgel,

Tópico(s)

COVID-19 Impact on Reproduction

Resumo

Zinc sulfide-coated copper indium sulfur selenide (CuInSexS2–x/ZnS core/shell) nanocrystals were synthesized with size-tunable red to near-infrared (NIR) fluorescence with high quantum yield (40%) in water. These nanocrystals were tested as an imaging agent to track a microparticle-based oral vaccine administered to mice. Poly(lactic-co-glycolic acid) (PLGA) microparticle-encapsulated CuInSexSe2–x/ZnS quantum dots were orally administered to mice and were found to provide a distinct visible fluorescent marker in the gastrointestinal tract of living mice.

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