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The First Total Synthesis of (Corrected) Ritterazine M

2002; American Chemical Society; Volume: 4; Issue: 3 Linguagem: Inglês

10.1021/ol016572l

1523-7060

Seongmin Lee, P. L. Fuchs,

Phytochemical Studies and Bioactivities

Hecogenin acetate was converted to ritterazine M in 16 operations with an average yield per opearation of 87%. The overall linear yield was 12%. This confirmed 1 as the corrected structure for ritterazine M by total synthesis.