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Hyperglycaemic effects of dopamine in tiger shrimp, Penaeus monodon

1995; Elsevier BV; Volume: 135; Issue: 1-3 Linguagem: Inglês

10.1016/0044-8486(95)01011-4

1873-5622

Ching-Ming Kuo, Chin-rong Hsu, Chung‐Yen Lin,

Aquaculture Nutrition and Growth

The presence and the physiological functions of biogenic amines as neuroregulators mediating the release of neurohormones have been documented in crustaceans. The possible involvement and the stimulatory pathway of dopamine in hyperglycaemia of the tiger shrimp, Penaeus monodon, were investigated. Two isoforms of crustacean hyperglycaemic hormone (CHH), CHH1 and CHH2, were identified. They were equally potent in the diabetic effect, and showed a great similarity in their amino acid composition profile, which is however, distinct from those reported from other crustacean species, such as the shore crab, Mexican crayfish and American lobster. Thus, species variation in the amino acid composition of CHH exists among the crustaceans. Dopamine was found to mimic the action of CHH in inducing hyperglycaemia in intact shrimps, but not in bilaterally eyestalk-ablated individuals. The hyperglycaemic response of shrimps that were treated with the agonist and antagonist to D1 and D2 receptors, suggest that dopamine functions as a neuroregulator, which in turn stimulates the release of CHH mainly through D1 receptors in tiger shrimps.