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Complete Genome Sequence of a thermotolerant sporogenic lactic acid bacterium, Bacillus coagulans strain 36D1

2011; Springer Science+Business Media; Volume: 5; Issue: 3 Linguagem: Inglês

10.4056/sigs.2365342

1944-3277

Mun Su Rhee, Brélan E. Moritz, Gary Xie, Tijana Glavina Del Rio, Eileen Dalin, Hope Tice, David Bruce, Lynne Goodwin, Olga Chertkov, Thomas Brettin, C. S. Han, Chris Detter, Sam Pitluck, Miriam Land, Milind Patel, Mark Ou, Roberta Harbrucker, L. O. Ingram, K. T. Shanmugam,

Enzyme Production and Characterization

Bacillus coagulans is a ubiquitous soil bacterium that grows at 50-55 °C and pH 5.0 and ferments various sugars that constitute plant biomass to L (+)-lactic acid. The ability of this sporogenic lactic acid bacterium to grow at 50-55 °C and pH 5.0 makes this organism an attractive microbial biocatalyst for production of optically pure lactic acid at industrial scale not only from glucose derived from cellulose but also from xylose, a major constituent of hemicellulose. This bacterium is also considered as a potential probiotic. Complete genome sequence of a representative strain, B. coagulans strain 36D1, is presented and discussed.