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Efficient Multicomponent Reaction Synthesis of the Schistosomiasis Drug Praziquantel

2010; Wiley; Volume: 16; Issue: 41 Linguagem: Inglês

10.1002/chem.201002046

1521-3765

Hai‐Ping Cao, Haixia Liu, Alexander Dömlingꝉ,

Pneumocystis jirovecii pneumonia detection and treatment

Shorter than ever: A convergent, efficient, and scalable access based on a key Ugi four-component reaction (4CR) followed by a Pictet–Spengler reaction comprises the shortest known synthesis to the schistosomiasis drug praziquantel (see scheme). Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.