Selenium status of industrial worker
1983; Elsevier BV; Volume: 3; Issue: 6 Linguagem: Inglês
10.1016/s0271-5317(83)80034-7
ISSN1879-0739
AutoresHelen W. Lane, Doris C. Warren, Elaine Martin, Jeanne McCowan,
Tópico(s)Body Composition Measurement Techniques
ResumoThe purpose of this study was to assess the selenium status of a well-defined industrially employed population: eighty-six oil refinery workers. Plasma selenium levels and erythrocyte GSH-Px activities were significantly lower in this industrial group (86 subjects) than in non-industrial group (174 subjects). In order to evaluate whether these lower values were responsive to supplementation, ten subjects from the industrial group were further studied for 12 weeks. Five of these subjects consumed a selenium supplement, 50 μg Se as sodium selenite, once a day for eight weeks (weeks 2 to 10 of study). Diet histories revealed that these 10 workers consumed an average of 217±73 μg Se/day indicating that they were consuming selenium levels above the recommendations of the Food and Nutrition Board of the NRC. The supplemented group had significantly higher whole blood selenium levels and GSH-Px activity than the non-supplemented group and this difference was due to a drop in the levels found in the non-supplemented group at weeks 8 and 10. These data suggest that selenium supplementation prevented the decreases in blood selenium levels and GSH-Px activity experienced by the non-supplemented subjects. Also, there was a positive correlation between blood selenium levels and GSH-Px (r=0.45, p<0.001). Thus, these oil refinery workers maintained GSH-Px activity only when consuming a selenium supplement suggesting that these workers may have a higher selenium need than any previously studied populations.
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