Portal de Periódicos da CAPES

Direct observation of key intermediates by negative-ion electrospray ionisation mass spectrometry in palladium-catalysed cross-coupling

2010; Royal Society of Chemistry; Volume: 46; Issue: 39 Linguagem: Inglês

10.1039/c0cc02773a

1364-548X

Krista L. Vikse, Matthew A. Henderson, Allen G. Oliver, J. Scott McIndoe,

Catalytic Cross-Coupling Reactions

Negative-ion electrospray ionisation mass spectrometry with an anionic phosphine ligand enables detection of key intermediates in the Sonogashira reaction. MS/MS techniques are used to generate a Hammett plot for the key reductive elimination step.