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Report on the fourth International workshop on reactive arthritis

2000; Wiley; Volume: 43; Issue: 4 Linguagem: Inglês

10.1002/1529-0131(200004)43

1529-0131

Joachim Sieper, J. Braun, Gabrielle Kingsley,

Systemic Lupus Erythematosus Research

Arthritis & RheumatismVolume 43, Issue 4 p. 720-734 Special ArticleFree to Read Report on the fourth International workshop on reactive arthritis Joachim Sieper, Corresponding Author Joachim Sieper University Hospital Benjamin Franklin, and German Rheumatology Research Center, Berlin, GermanyRheumatology, Department of Medicine, University Hospital Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, GermanySearch for more papers by this authorJürgen Braun, Jürgen Braun University Hospital Benjamin Franklin, Berlin, GermanySearch for more papers by this authorGabrielle H. Kingsley, Gabrielle H. Kingsley Guy's, King's, and St. Thomas' School of Medicine, London, UKSearch for more papers by this author Joachim Sieper, Corresponding Author Joachim Sieper University Hospital Benjamin Franklin, and German Rheumatology Research Center, Berlin, GermanyRheumatology, Department of Medicine, University Hospital Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, GermanySearch for more papers by this authorJürgen Braun, Jürgen Braun University Hospital Benjamin Franklin, Berlin, GermanySearch for more papers by this authorGabrielle H. Kingsley, Gabrielle H. Kingsley Guy's, King's, and St. Thomas' School of Medicine, London, UKSearch for more papers by this author First published: 02 April 2001 https://doi.org/10.1002/1529-0131(200004)43:4 3.0.CO;2-8Citations: 78AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES 1 Szalay G, Ladel CH, Blum C, Brossay L, Kronenberg M, Kaufmann SH. Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-β2 and Th1 cytokines and ameliorates listeriosis in mice. J Immunol 1999; 162: 6955– 8. 2 Zugel U, Schoel B, Yamamoto S, Hengel H, Morein B, Kaufmann SH. Crossrecognition by CD8 T cell receptor αβ cytotoxic T lymphocytes of peptides in the self and the mycobacterial hsp60 which share intermediate sequence homology. Eur J Immunol 1995; 25: 451– 8. 3 Zhang Y, Gripenberg-Lerche C, Söderström K-O, Toivanen A, Toivanen P. Antibiotic prophylaxis and treatment of reactive arthritis: lessons from an animal model. Arthritis Rheum 1996; 39: 1238– 43. 4 Wilkinson NZ, Kingsley GH, Jones HW, Sieper J, Braun J, Ward ME. The detection of DNA from a range of bacterial species in the joints of patients with a variety of arthritides using a nested, broad-range polymerase chain reaction. Rheumatology 1999; 38: 260– 6. 5 Toivanen A, Lahesmaa-Rantala R, Vuento R, Granfors K. Association of persisting IgA response with yersinia triggered reactive arthritis: a study on 104 patients. Ann Rheum Dis 1987; 46: 898– 901. 6 Granfors K, Merilahti-Palo R, Luukkainen R, Möttönen T, Lahesmaa R, Probst P, et al. Persistence of Yersinia antigens in peripheral blood cells from patients with Yersinia enterocolitica O:3 infection with or without reactive arthritis. Arthritis Rheum 1998; 41: 855– 62. 7 Kirveskari J, Jalkanen S, Mäki-Ikola O, Granfors K. Increased synovial endothelium binding and transendothelial migration of mononuclear cells during Salmonella infection. Arthritis Rheum 1998; 41: 1054– 63. 8 Granfors K, Jalkanen S, Toivanen P, Koski J, Lindberg AA. Bacterial lipopolysaccharide in synovial fluid cells in Shigella triggered reactive arthritis [letter]. J Rheumatol 1992; 19: 500. 9 Stieglitz H, Lipsky P. Association between reactive arthritis and antecedent infection with Shigella flexneri carrying a 2-Md plasmid and encoding an HLA–B27 mimetic epitope. Arthritis Rheum 1993; 36: 1387– 91. 10 Bas S, Scieux C, Vischer TL. Different humoral immune response to Chlamydia trachomatis major outer membrane protein variable domains I and IV in Chlamydia-infected patients with or without reactive arthritis. Arthritis Rheum 1999; 42: 942– 7. 11 Stephens RS, Kalman S, Lammel C, Fan J, Marathe R, Aravind L, et al. Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science 1998; 282: 754– 9. 12 Inman RD, Chiu B. Synoviocyte-packaged Chlamydia trachomatis induces a chronic aseptic arthritis. J Clin Invest 1998; 102: 1776– 82. 13 Bas S, Griffais R, Kvien TK, Glennås A, Melby K, Vischer TL. Amplification of plasmid and chromosome Chlamydia DNA in synovial fluid of patients with reactive arthritis and undifferentiated seronegative oligoarthropathies. Arthritis Rheum 1995; 38: 1005– 13. 14 Branigan PJ, Gérard HC, Hudson AP, Schumacher HR Jr, Pando J. Comparison of synovial tissue and synovial fluid as the source of nucleic acids for detection of Chlamydia trachomatis by polymerase chain reaction [published errata appear in Arthritis Rheum 1997;40:387 and 1997;40:782]. Arthritis Rheum 1996; 39: 1740– 6. 15 Wilkinson NZ, Kingsley GH, Sieper J, Braun J, Ward ME. Lack of correlation between the detection of Chlamydia trachomatis DNA in synovial fluid from patients with a range of rheumatic diseases and the presence of an antichlamydial immune response. Arthritis Rheum 1998; 41: 845– 54. 16 Gerard HC, Branigan PJ, Schumacher HR Jr, Hudson AP. Synovial Chlamydia trachomatis in patients with reactive arthritis/Reiter's syndrome are viable but show aberrant gene expression. J Rheumatol 1998; 25: 734– 42. 17 Schumacher HR Jr, Arayssi T, Crane M, Lee J, Gerard H, Hudson AP, et al. Chlamydia trachomatis nucleic acids can be found in the synovium of some asymptomatic subjects. Arthritis Rheum 1999; 42: 1281– 4. 18 Lau CS, Burgos-Vargas R, Louthrenoo W, Mok MY, Wordsworth P, Zeng QY. Features of spondyloarthritis around the world. Rheum Dis Clin North Am 1998; 24: 753– 70. 19 Khan MA. Epidemiology of HLA-B27 and arthritis. Clin Rheumatol 1996; 15 Suppl 1: 10– 2. 20 Brown MA, Kennedy LG, MacGregor AJ, Darke C, Duncan E, Shatford JL, et al. Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. Arthritis Rheum 1997; 40: 1823– 8. 21 Brown MA, Pile KD, Kennedy LG, Campbell D, Andrew L, March R, et al. A genome-wide screen for susceptibility loci in ankylosing spondylitis. Arthritis Rheum 1998; 41: 588– 95. 22 Sieper J, Braun J. Pathogenesis of spondylarthropathies: persistent bacterial antigen, autoimmunity, or both? Arthritis Rheum 1995; 38: 1547– 54. 23 Allen RL, O'Callaghan CA, McMichael AJ, Bowness P. Cutting edge: HLA-B27 can form a novel β2-microglobulin-free heavy chain homodimer structure. J Immunol 1999; 162: 5045– 8. 24 Onderdonk AB, Richardson JA, Hammer RE, Taurog JD. Correlation of cecal microflora of HLA-B27 transgenic rats with inflammatory bowel disease. Infect Immun 1998; 66: 6022– 3. 25 Rath HC, Wilson KH, Sartor RB. Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect Immun 1999; 67: 2969– 74. 26 Zhou M, Sayad A, Simmons WA, Jones RC, Maika SD, Satumtira N, et al. The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLA-B27 transgenic rats. J Exp Med 1998; 188: 877– 86. 27 Falgarone G, Blanchard HS, Virecoulon F, Simonet M, Breban M. Coordinate involvement of invasin and Yop proteins in a Yersinia pseudotuberculosis-specific class I-restricted cytotoxic T cell-mediated response. J Immunol 1999; 162: 2875– 83. 28 Khare SD, Luthra HS, David CS. Animal models of human leukocyte antigen B27-linked arthritides. Rheum Dis Clin North Am 1998; 24: 883– 94. 29 Khare SD, Bull MJ, Hanson J, Luthra HS, David CS. Spontaneous inflammatory disease in HLA-B27 transgenic mice is independent of MHC class II molecules: a direct role for B27 heavy chains and not B27-derived peptides. J Immunol 1998; 160: 101– 6. 30 Bohn E, Autenrieth IB. IL-12 is essential for resistance against Yersinia enterocolitica by triggering IFN-γ production in NK cells and CD4+ T cells. J Immunol 1996; 156: 1458– 68. 31 Yang X, Gartner J, Zhu L, Wang S, Brunham RC. IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J Immunol 1999; 162: 1010– 7. 32 Yin Z, Siegert S, Neure L, Grolms M, Liu L, Eggens U, et al. The elevated ratio of IFNγ-/IL-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by IL-4 but not by IL-10 or TGF. Rheumatology 1999; 38: 1058– 67. 33 Braun J, Yin Z, Spiller I, Siegert S, Rudwaleit M, Liu L, et al. Low secretion of tumor necrosis factor α, but no other Th1 or Th2 cytokines, by peripheral blood mononuclear cells correlates with chronicity in reactive arthritis. Arthritis Rheum 1999; 42: 2039– 44. 34 Yin Z, Braun J, Neure L, Wu P, Liu L, Eggens U, et al. Crucial role of interleukin-10/interleukin-12 balance in the regulation of the type 2 T helper cytokine response in reactive arthritis. Arthritis Rheum 1997; 40: 1788– 97. 35 Kotake S, Schumacher HR Jr, Arayssi TK, Gerard HC, Branigan PJ, Hudson AP, et al. Gamma interferon and interleukin-10 gene expression in synovial tissues from patients with early stages of Chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. Infect Immun 1999; 67: 2682– 6. 36 Tuokko J, Koskinen S, Westman P, Yli-Kerttula U, Toivanen A, Ilonen J. Tumour necrosis factor microsatellites in reactive arthritis. Br J Rheumatol 1998; 37: 1203– 6. 37 Pociot F, Briant L, Jongeneel CV, Molvig J, Worsaae H, Abbal M, et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 1993; 23: 224– 31. 38 Höhler T, Schäper T, Schneider PM, Meyer zum B üschenfelde K-H, Märker-Hermann E. Association of different tumor necrosis factor α promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals. Arthritis Rheum 1998; 41: 1489– 92. 39 McGarry F, Walker R, Sturrock R, Field M. The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27. J Rheumatol 1999; 26: 1110– 6. 40 Wilson AG, Symons JA, McDowell TL, McDevitt HO, Duff GW. Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation. Proc Natl Acad Sci U S A 1997; 94: 3195– 9. 41 Eskdale J, Gallagher G, Verweij CL, Keijsers V, Westendorp RG, Huizinga TW. Interleukin 10 secretion in relation to human IL-10 locus haplotypes. Proc Natl Acad Sci U S A 1998; 95: 9465– 70. 42 Keijsers V, Tong TQT, Verweij CL, Hazes M, Westendorp RGJ, Breedveld FC, et al. Innate differences in IL-10 production are present at the level of transcription and associated with haplotypes: association of IL-10 haplotypes and rheumatoid arthritis [abstract]. Arthritis Rheum 1998; 41 Suppl 9: S188. 43 Crawley E, Kay R, Sillibourne J, Patel P, Hutchinson I, Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum 1999; 42: 1101– 8. 44 Deane KH, Jecock RM, Pearce JH, Gaston JS. Identification and characterization of a DR4-restricted T cell epitope within chlamydia heat shock protein 60. Clin Exp Immunol 1997; 109: 439– 45. 45 Mertz AKH, Ugrinovic S, Lauster R, Wu P, Grolms M, Böttcher U, et al. Characterization of the synovial T cell response to various recombinant Yersinia antigens in Yersinia enterocolitica–triggered reactive arthritis: heat-shock protein 60 drives a major immune response. Arthritis Rheum 1998; 41: 315– 26. 46 Ugrinovic S, Mertz A, Wu P, Braun J, Sieper J. A single nonamer from the Yersinia 60-kDa heat shock protein is the target of HLA-B27-restricted CTL response in Yersinia-induced reactive arthritis. J Immunol 1997; 159: 5715– 23. 47 Van Eden W, van der Zee R, Paul AG, Prakken BJ, Wendling U, Anderton SM, et al. Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases? Immunol Today 1998; 19: 303– 7. 48 Duchmann R, May E, Heike M, Knolle P, Neurath M, Meyer zum Buschenfelde KH. T cell specificity and cross reactivity towards enterobacteria, bacteroides, bifidobacterium, and antigens from resident intestinal flora in humans. Gut 1999; 44: 812– 8. 49 May E, Märker-Hermann E, Meyer zum Büschenfelde K-H, Duchmann R. Detection and isolation of identical clonally expanded CD8+ T cells in the colon and the synovium of a HLA-B27+ patient with colitis and subsequent arthritis [abstract]. J Rheumatol 1998; 25 Suppl 54: 22. 50 Hermann E, Yu DT, Meyer zum Buschenfelde KH, Fleischer B. HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis. Lancet 1993; 342: 646– 50. 51 Dulphy N, Peyrat MA, Tieng V, Douay C, Rabian C, Tamouza R, et al. Common intra-articular T cell expansions in patients with reactive arthritis: identical β-chain junctional sequences and cytotoxicity toward HLA-B27. J Immunol 1999; 162: 3830– 9. 52 Braun J, Bollow M, Sieper J. Radiologic diagnosis and pathology of the spondyloarthropathies. Rheum Dis Clin North Am 1998; 24: 697– 735. 53 McGonagle D, Gibbon W, O'Connor P, Green M, Pease C, Emery P. Characteristic magnetic resonance imaging entheseal changes of knee synovitis in spondylarthropathy. Arthritis Rheum 1998; 41: 694– 700. 54 Sieper J, Braun J. Treatment of reactive arthritis with antibiotics. Br J Rheumatol 1998; 37: 717– 20. 55 Mattila L, Leirisalo-Repo M, Pelkonen P, Koskimies S, Granfors K, Siitonen A. Reactive arthritis following an outbreak of Salmonella bovismorbificans infection. J Infect 1998; 36: 289– 95. 56 Lauhio A, Leirisalo-Repo M, Lähdevirta J, Saikku P, Repo H. Double-blind, placebo-controlled study of three-month treatment with lymecycline in reactive arthritis, with special reference to Chlamydia arthritis. Arthritis Rheum 1991; 34: 6– 14. 57 Toivanen A, Yli-Kerttula T, Luukkainen R, Merilahti-Palo R, Granfors K, Seppala J. Effect of antimicrobial treatment on chronic reactive arthritis. Clin Exp Rheumatol 1993; 11: 301– 7. 58 Sieper J, Fendler C, Laitko S, Sörensen H, Gripenberg-Lerche C, Hiepe F, et al. No benefit of long-term ciprofloxacin treatment in patients with reactive arthritis and undifferentiated oligoarthritis: a three-month, multicenter, double-blind, randomized, placebo-controlled study. Arthritis Rheum 1999; 42: 1386– 96. 59 Kerttula Y, Luukainen R, Yli-Kerttula U, Möttönen T, Hakola M, Korpela M, et al. Effect of a three month course of ciprofloxacin on reactive arthritis [abstract]. Ann Rheum Dis 1999; 58 Suppl: P122. 60 Leirisalo-Repo M. Prognosis, course of disease, and treatment of the spondyloarthropathies. Rheum Dis Clin North Am 1998; 24: 737– 51. 61 Sieper J, Braun J. Problems and advances in the diagnosis of reactive arthritis. J Rheumatol 1999; 26: 1222– 4. 62 Inman RD. Classification criteria for reactive arthritis. J Rheumatol 1999; 26: 1219– 21. 63 Kingsley G, Sieper J. Third International Workshop on Reactive Arthritis: 23–26 September 1995, Berlin, Germany. Report and abstracts. Ann Rheum Dis 1996; 55: 564– 84. 64 Rao JK, Allen NB, Pincus T. Limitations of the 1990 American College of Rheumatology classification criteria in the diagnosis of vasculitis. Ann Intern Med 1998; 129: 345– 52. 65 Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315– 24. 66 Dougados M, van der Linden S, Juhlin R, Huitfeldt B, Amor B, Calin A, et al. The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 1991; 34: 1218– 27. 67 Maki-Ikola O, Lahesmaa R, Heesemann J, Merilahti-Palo R, Saario R, Toivanen A, et al. Yersinia-specific antibodies in serum and synovial fluid in patients with Yersinia triggered reactive arthritis. Ann Rheum Dis 1994; 53: 535– 9. 68 Isomaki O, Vuento R, Granfors K. Serological diagnosis of salmonella infections by enzyme immunoassay. Lancet 1989; 1: 1411– 4. 69 Bas S, Vischer TL. Chlamydia trachomatis antibody detection and diagnosis of reactive arthritis. Br J Rheumatol 1998; 37: 1054– 9. 70 Kuipers JG, Jürgens-Saathoff B, Bialowons A, Wollenhaupt J, Köhler L, Zeidler H. Detection of Chlamydia trachomatis in peripheral blood leukocytes of reactive arthritis patients by polymerase chain reaction. Arthritis Rheum 1998; 41: 1894– 5. 71 Kuipers JG, Nietfeld L, Dreses-Werringloer U, Koehler L, Wollenhaupt J, Zeidler H, et al. Optimised sample preparation of synovial fluid for detection of Chlamydia trachomatis DNA by polymerase chain reaction. Ann Rheum Dis 1999; 58: 103– 8. Citing Literature Volume43, Issue4April 2000Pages 720-734 ReferencesRelatedInformation