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Anti-stress and Anti-fatigue Effects of Fermented Rice Bran

2001; Oxford University Press; Volume: 65; Issue: 10 Linguagem: Inglês

10.1271/bbb.65.2294

1347-6947

Kyung-Mi Kim, Kwang Won Yu, Duk Ho Kang, Jong Ho Koh, Bum Shik Hong, Hyung Joo Suh,

Healthcare and Venom Research

The anti-stress and anti-fatigue effects on rats and mice of a hot water extract of rice bran fermented with Saccharomyces cerevisae IFO 2346 were investigated. Oral administration (1 g/kg/day) of the hot water extract of fermented rice bran (FRB) inhibited major changes in the weight of the adrenal, thymus, spleen and thyroid, showing an anti-stress effect. The hot water extract of FRB also inhibited increases in the GPT and LDH activity, cholesterol and glucose in the serum. The administration (1 g/kg/day) for 2 weeks significantly prolonged the swimming time, resulting in an increase in the anti-fatigue effect. It is considered from these results that FRB had anti-stress and anti-fatigue effects.